| Date | Location | Result | |
| 11-10-07 | Defiance, OH | Bluffton University 22, Defiance College 21 | Box score |
| 11-03-07 | Franklin, Ind. | Franklin College 55, Defiance College 22 | Box score |
| 10-27-07 | Cincinnati, OH | Mount St. Joseph 10, Defiance College 0 | Box score |
| 10-20-07 | Defiance, OH | Defiance College 33, Hanover College 7 | Box score |
| 10-13-07 | Anderson, IN | Defiance College 34, Anderson University 7 | Box score |
| 10-06-07 | Defiance, OH | Defiance College 33, Rose-Hulman 31 | Box score |
| 09-29-07 | Defiance, OH | Defiance College 27, Manchester College 8 | Box score |
| 09-15-07 | Angola,IN | Tri-State University 17, Defiance College 13 | Box score |
| 09-08-07 | Westerville, OH | Defiance College 16, Otterbein College 14 | Box score |
| 09-01-07 | Defiance, OH | Adrian College 35, Defiance College 9 | Box score |