| Date | Location | Result | |
| 03-01-08 | Defiance, OH | Franklin 82, Defiance College 76 | Box score |
| 02-29-08 | Defiance, OH | Defiance College 95, Anderson 86 | Box score |
| 02-29-08 | Defiance, OH | Franklin 60, Transylvania 53 | Box score |
| 02-23-08 | Defiance, OH | Rose-Hulman 43, Defiance College 42 | Box score |
| 02-20-08 | Franklin, IN | Defiance College 68, Franklin 61 | Box score |
| 02-16-08 | Defiance, OH | Defiance College 64, Transylvania 59 | Box score |
| 02-13-08 | N. Manchester, IN | Defiance College 79, Manchester 71 | Box score |
| 02-09-08 | Terre Haute, IN | Defiance College 57, Rose-Hulman 40 | Box score |
| 02-02-08 | Cincinnati, OH | Mount St. Joseph 70, Defiance College 63 | Box score |
| 01-30-08 | Defiance, OH | Defiance College 90, Bluffton 71 | Box score |
| 01-26-08 | Defiance, OH | Defiance College 58, Hanover 49 | Box score |
| 01-23-08 | Defiance, OH | Defiance College 68, Manchester 46 | Box score |
| 01-19-08 | Anderson, IN | Defiance College 72, Anderson 53 | Box score |
| 01-16-08 | Defiance, OH | Franklin 76, Defiance College 66 | Box score |
| 01-12-08 | Lexington, KY | Defiance College 98, Transylvania 65 | Box score |
| 01-05-08 | Defiance, OH | Defiance College 88, Mount St. Joseph 64 | Box score |
| 12-30-07 | Defiance, OH | Defiance College 99, Tri-State 61 | Box score |
| 12-30-07 | Defiance, OH | Loras 73, Thiel 59 | Box score |
| 12-29-30 | Defiance, OH | Defiance College 69, Thiel 49 | Box score |
| 12-29-30 | Defiance, OH | Tri-State 66, Loras 65 | Box score |
| 12-19-07 | Orlando, FL | Roanoke 69, Defiance College 68 | Box score |
| 12-18-07 | Orlando, FL | Defiance College 53, UW-Oshkosh 46 | Box score |
| 12-08-07 | Hanover, IN | Defiance College 70, Hanover 54 | Box score |
| 12-05-07 | Bluffton, OH | Defiance College 86, Bluffton 70 | Box score |
| 12-01-07 | Defiance, OH | Defiance College 74, Anderson 67 | Box score |
| 11-28-07 | Defiance, OH | Ohio Wesleyan 68, Defiance College 67 | Box score |
| 11-25-07 | Kalamazoo, MI | Defiance 79, Kalamazoo 69 | Box score |
| 11-20-07 | Defiance, OH | Heidelberg 86, Defiance College 74 | Box score |
| 11-17-07 | Crestview Hills, KY | Defiance 65, Thomas More 59 | Box score |
| 11-15-07 | Crestview Hills, KY | Wilmington 59, Defiance 57 | Box score |